Transcription factories in a Hela cell [from Cook PR (1999) Science 284, 1790]

Nuclear Structure and Function Research Group

Model for all genomes Welcome to the Cook group (contacts).

'Microfluidics with fluid walls': 'Freestyle Fluidics' (pdf; large pdf with embedded movies) - a platform we hope will transform the way small volumes are handled. is commercializing this technology.


'Why the activity of a gene depends on its neighbors': a mini-review outlining how genomes are organized, and how genes are regulated.


Movie: This 5-min YouTube movie shows how we think an RNA polymerase works, how genes are regulated, and how the genome is organized.

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