Publications

2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | Earlier than 2000 | Reviews

2015 ^

Sunter, J., Varga, V., Dean, S. & Gull, K. (2015). A dynamic co-ordination of flagellum and cytoplasmic cytoskeleton assembly specifies cell morphogenesis in trypanosomes. Journal of Cell Science 128, 1580-94 (PDF)

Dean, S., Sunter, J., Wheeler, R. J., Hodkinson, I., Gluenz, E. & Gull, K. (2015).
A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids. Open Biol 5. (doi:10.1098/rsob.140197) (PDF)

2014 ^

Hayes P., Varga V., Olego-Fernandez S., Sunter J., Ginger M.L., Gull K. (2014). Modulation of a cytoskeletal calpain-like protein induces major transitions in trypanosome morphology. J Cell Biol. 206, 377-384. (PDF)

Portman N. and Gull K. (2014). Identification of Paralogous Life-Cycle Stage Specific Cytoskeletal Proteins in the Parasite Trypanosoma brucei. PLoS ONE 9(9):e106777. (PDF)

Brown R. W. B., Collingridge P. W., Gull K., Rigden D. J., Ginger M. L. (2014) Evidence for Loss of a Partial Flagellar Glycolytic Pathway during Trypanosomatid Evolution. PLoS ONE 9(7): e103026. (PDF)

Höög, J. L., Lacomble, S., O'Toole, E. T., Hoenger, A., McIntosh, J. R. and Gull, K. (2014). Modes of flagellar assembly in Chlamydomonas reinhardtii and Trypanosoma brucei. eLife 3, e01479. (PDF)

Akiyoshi, B. and Gull, K. (2014). Discovery of unconventional kinetochores in kinetoplastids. Cell 156, 1247-58. (PDF)

2013 ^

Wheeler, R. J., Scheumann, N., Wickstead, B., Gull, K. and Vaughan, S. (2013). Cytokinesis in Trypanosoma brucei differs between bloodstream and tsetse trypomastigote forms: implications for microtubule-based morphogenesis and mutant analysis. Molecular Microbiology 90, 1339-55.(PDF)

Wheeler, R. J., Gluenz, E. and Gull, K. (2013). The limits on trypanosomatid morphological diversity. PLoS One 8, e79581. (PDF)

Povelones, M. L., Tiengwe, C., Gluenz, E., Gull, K., Englund, P. T. and Jensen, R. E. (2013). Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1. Molecular Microbiology 87, 713-29.(PDF)

Hughes, L., Towers, K., Starborg, T., Gull, K. and Vaughan, S. (2013). A cell-body groove housing the new flagellum tip suggests an adaptation of cellular morphogenesis for parasitism in the bloodstream form of Trypanosoma brucei. Journal of Cell Science 126, 5748-57. (PDF)

Ginger, M. L., Collingridge, P. W., Brown, R. W., Sproat, R., Shaw, M. K. and Gull, K. (2013). Calmodulin is required for paraflagellar rod assembly and flagellum-cell body attachment in trypanosomes. Protist 164, 528-40.(PDF)

de Leon, J. C., Scheumann, N., Beatty, W., Beck, J. R., Tran, J. Q., Yau, C., Bradley, P. J., Gull, K., Wickstead, B. and Morrissette, N. S. (2013). A SAS-6-like protein suggests that the Toxoplasma conoid complex evolved from flagellar components. Eukaryotic Cell 12, 1009-19. (PDF)

Akiyoshi, B. and Gull, K. (2013). Evolutionary cell biology of chromosome segregation: insights from trypanosomes. Open Biology 3, 130023. (PDF)

2012 ^

Povelones, M. L., Gluenz, E., Dembek, M., Gull, K. and Rudenko, G. (2012). Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei. PLOS Pathogens 8, e1003010. (PDF)

Kelly, S., Kramer, S., Schwede, A., Maini, P. K., Gull, K. and Carrington, M. (2012). Genome organization is a major component of gene expression control in response to stress and during the cell division cycle in trypanosomes. Open Biology 2, 120033. (PDF)

Adams, M., Simms, R. J., Abdelhamed, Z., Dawe, H. R., Szymanska, K., Logan, C. V., Wheway, G., Pitt, E., Gull, K., . . Johnson, C. A. (2012). A meckelin-filamin A interaction mediates ciliogenesis. Hum. Mol. Genet, 21(6), 1272-1286. (PDF)

Lacomble, S., Vaughan, S., Deghelt, M., Moreira-Leite, F. F., & Gull, K. (2012). A Trypanosoma brucei protein required for maintenance of the flagellum attachment zone and flagellar pocket ER domains. Protist, 163(4), 602-615. (PDF)

Sunter, J., Wickstead, B., Gull, K., & Carrington, M. (2012). A new generation of T7 RNA polymerase-independent inducible expression plasmids for Trypanosoma brucei. PLoS One, 7(4), e35167. (PDF)

Wheeler, R. J., Gull, K., & Gluenz, E. (2012). Detailed interrogation of trypanosome cell biology via differential organelle staining and automated image analysis. BMC Biol, 10, 1. (PDF)

Höög, J. L., Bouchet-Marquis, C., McIntosh, J. R., Hoenger, A., & Gull, K. (2012). Cryo-electron tomography and 3-D analysis of the intact flagellum in Trypanosoma brucei. J Struct Biol, 178(2), 189-198. (PDF)

Poon, S. K., Peacock, L., Gibson, W., Gull, K., & Kelly, S. (2012). A modular and optimized single marker system for generating Trypanosoma brucei cell lines expressing T7 RNA polymerase and the tetracycline repressor. Open Biology, 2(2). (PDF)

Daniels, J. P., Gull, K., & Wickstead, B. (2012). The trypanosomatid-specific N terminus of RPA2 is required for RNA polymerase I assembly, localization, and function. Eukaryot Cell, 11(5), 662-672. (PDF)

Portman, N., & Gull, K. (2012). Proteomics and the Trypanosoma brucei cytoskeleton: advances and opportunities. Parasitology, 139(9), 1168-1177. (PDF)

Tiengwe, C., Marcello, L., Farr, H., Dickens, N., Kelly, S., Swiderski, M., Vaughan, D., Gull, K., . . . McCulloch, R. (2012). Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei. Cell Reports, 2(1), 185-197. (PDF)

2011 ^

Wickstead, B. & Gull, K. (2011) Evolution: the evolution of the cytoskeleton. J. Cell Biol. 194(4), 513-525 (PDF)

Gluenz, E., Barker, A.R., & Gull, K. (2011) An expanded family of proteins with BPI/LBP/PLUNC-like domains in trypanosome parasites: an association with pathogenicity? Biochem Soc Trans. 39(4), 966-970.

Wheeler, R. J., Gluenz, E. and Gull, K. (2011) The cell cycle of Leishmania: morphogenetic events and their implications for parasite biology. Mol Microbiol. 79, 647-662 (PDF)

Gluenz, E., Povelones, M. L., Englund, P. T. and Gull, K. (2011) The Kinetoplast Duplication Cycle in Trypanosoma brucei Is Orchestrated by Cytoskeleton-Mediated Cell Morphogenesis. Mol Cell Biol. 31, 1012-1021. (PDF)

Clayton, A. M., Guler, J. L., Povelones, M. L., Gluenz, E., Gull, K., Smith, T. K., Jensen, R. E. and Englund, P. T. (2011) Depletion of mitochondrial acyl carrier protein in bloodstream form Trypanosoma brucei causes a kinetoplast segregation defect. Eukaryot Cell, 10(3) 286 (PDF)

Kelly, S., Wickstead, B., Maini, P. K., & Gull, K. (2011). Ab initio identification of novel regulatory elements in the genome of Trypanosoma brucei by Bayesian inference on sequence segmentation. PLoS ONE, 6(10) (PDF)

Hodges, M. E., Wickstead, B., Gull, K., & Langdale, J. A. (2011). Conservation of ciliary proteins in plants with no cilia. BMC Plant Biol, 11, 185. (PDF)

2010 ^

Wickstead, B., Gull, K. and Richards, T. A. (2010) Patterns of kinesin evolution reveal a complex ancestral eukaryote with a multifunctional cytoskeleton. BMC Evol Biol. 10, 110 (PDF)

Wickstead, B., Carrington, J. T., Gluenz, E. and Gull, K. (2010) The expanded Kinesin-13 repertoire of trypanosomes contains only one mitotic Kinesin indicating multiple extra-nuclear roles. PLoS One. 5, e15020 (PDF)

Lacomble, S., Vaughan, S., Gadelha, C., Morphew, M. K., Shaw, M. K., McIntosh, J. R. and Gull, K. (2010) Basal body movements orchestrate membrane organelle division and cell morphogenesis in Trypanosoma brucei. J Cell Sci. 123, 2884-2891 (PDF)

Kelly, S., Wickstead, B. and Gull, K. (2010) Archaeal phylogenomics provides evidence in support of a methanogenic origin of the Archaea and a thaumarchaeal origin for the eukaryotes. Proc Biol Sci (PDF)

Höög, J. L., Gluenz, E., Vaughan, S. and Gull, K. (2010) Ultrastructural investigation methods for Trypanosoma brucei. Methods Cell Biol. 96, 175-196.

Hodges, M. E., Scheumann, N., Wickstead, B., Langdale, J. A. and Gull, K. (2010) Reconstructing the evolutionary history of the centriole from protein components. J Cell Sci. 123, 1407-1413 (PDF)

Gluenz, E., Höög, J. L., Smith, A. E., Dawe, H. R., Shaw, M. K. and Gull, K. (2010) Beyond 9+0: noncanonical axoneme structures characterize sensory cilia from protists to humans. FASEB J. 24, 3117-3121 (PDF)

2009 ^

Farr H and Gull K. (2009) Functional studies of an evolutionarily conserved cytochrome b5 domane protein reveal a specific role in axonemal organisation and the general phenomenon of post-division axonemal growth in Trypanosomes. Cell Motility Cytoskeleton 66:24-35 (PDF)

Lacomble S, Vaughan S, Gadelha C, Morphew MK, Shaw MK, McIntosh JR, Gull K. (2009) Three-dimensional cellular architecture of the flagellar pocket and associated cytoskeleton in trypanosomes revealed by electron microscope tomography. J Cell Sci. 122(8):1081-90. (PDF)

Signorell A, Gluenz E, Rettig J, Schneider A, Shaw MK, Gull K, Bütikofer P. (2009) Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei. Mol Microbiol. 72(4):1068-79. (PDF)

Dawe HR, Adams M, Wheway G, Szymanska K, Logan CV, Noegel AA, Gull K, Johnson CA. (2009) Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. J Cell Sci. 122(15):2716-26 (PDF)

Daniels JP, Kelly S, Wickstead B, Gull K. (2009) Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea. Biol Direct. 4:24 (PDF)

Olego-Fernandez S, Vaughan S, Shaw MK, Gull K, Ginger ML. (2009) Cell morphogenesis of Trypanosoma brucei requires the paralogous, differentially expressed calpain-related proteins CAP5.5 and CAP5.5V. Protist. 160(4):576-90. (PDF)

Gadelha C, Rothery S, Morphew M, McIntosh JR, Severs NJ, Gull K. (2009) Membrane domains and flagellar pocket boundaries are influenced by the cytoskeleton in African trypanosomes. Proc Natl Acad Sci 106(41):17425-30 (PDF)

Smith T.K, Vasileva N, Gluenz E, Terry S, Portman N, Kramer S, Carrington M, Michaeli S, Gull K and Rudenko G. (2009) Blocking global Variant Surface Glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation. PLoS One 4 (10) (PDF)

Lacomble S, Portman N, Gull K. (2009) A protein-protein interaction map of the Trypanosoma brucei paraflagellar rod. PLoS One 4(11) (PDF)

2008 ^

Uzureau P, Daniels JP, Walgraffe D, Wickstead B, Pays E, Gull K, Vanhamme L. (2008) Identification and characterisation of two trypanosome TFIIS proteins exhibiting particular domain architectures and differential nuclear localisations. Mol Microbiol. (PDF)

Gluenz E, Sharma R, Carrington M, Gull K. (2008) Functional characterisation of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages. Mol Microbiol. (PDF)

Vaughan S, Gull K. (2008) The structural mechanics of cell division in Trypanosoma brucei. Biochem Soc Trans. 36(Pt 3):421-4.

Barker AR, Wickstead B, Gluenz E, Gull K. (2008) Bioinformatic insights to the ESAG5 and GRESAG5 gene families in Kinetoplastid parasites. Mol Biochem. Parisitol. 162: 112-122 (PDF)

Hart SR, Lau KW, Hao Z, Broadhead R, Portman N, Hühmer A, Gull K, McKean PG, Hubbard SJ, Gaskell SJ. (2008) Analysis of the trypanosome flagellar proteome using a combined electron transfer/collisionally activated dissociation strategy. J Am Soc Mass Spectrom. 20(2):167-75. (PDF)

Lindsay ME, Gluenz E, Gull K, Englund PT. (2008) A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology. Mol. Microbiol. 70 )6) 1465-1476 (PDF)

Portman N, Lacomble S, Thomas B, McKean PG, Gull K. (2008) Combining RNA interference mutants and comparative proteomics to identify protein components and dependences in a eukaryotic flagellum. J Biol Chem. 284(9):5610-9. (PDF)

2007 ^

Vaughan S, Kohl L, Ngai I, Wheeler R, and Gull K. A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei. (2007) (PDF)

Baines, A and Gull, K. (2007) WCB is a C2 domain protein defining plasma membrane - subpellicular microtubule corset interactions in kinetoplastid parasites. Protist. 159(1):115-25. (PDF)

Wickstead B & Gull K. (2007). Evolution of dyneins in eukaryotes. Traffic 8 (12) 1708-21 (PDF)

Sharma R, Gluenz E, Peacock L, Gibson W, Gull K and Carrington M. (2007) Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes. Protist 2007 Oct 9; (PDF)

Dawe H R, Shaw M K and Gull K (2007) The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules. BMC Biol 5: 33 (PDF)

Gluenz, E; Shaw, M and Gull K (2007) Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast. Molecular Microbiology 64 (6) 1529-1539. (PDF)

Griffiths S, Portman N, Taylor PR, Gordon S, Ginger ML, Gull K.. (2007) RNAi mutant induction in vivo demonstrates the essential nature of trypanosome flagellar function during mammalian infection. Eukaryotic Cell 6(7) 1248-50 (PDF)

Gadelha, C*., Wickstead, B*., and Gull, K. (2007). Trypanosome motility: flagellar and ciliary beating. Cell Motility and the Cytoskeleton 64 (8) 629-43 (PDF)

Stephan A*, Vaughan S*, Shaw M K, Gull K and McKean P G. (2007) An essential quality control mechanism at the eukaryotic basal body prior to intraflagellar transport. Traffic 8 (issue 10) 1323-30 (PDF)

Dawe, H., Farr, H., and Gull, K. (2007). Centriole / basal body morphogenesis and migration during ciligenesis in animal cells. Journal of Cell Science. 120 7-15. (PDF)

Steven Kelly, Jenny Reed, Susanne Kramer, Louise Ellis, Helena Webb, Jack Sunter, Jeanne Salje, Nina Marinsek, Keith Gull, Bill Wickstead and Mark Carrington. (2007) Functional genomics in Trypanosoma brucei: A collection of vectors for the expression of tagged proteins from endogenous and ectopic gene loci Molecular and Biochemical Parasitology 154 (1) 103-9. (PDF)

Dawe, H., Ursula, M., Smith, Andrew, R., Cullinane, Gerrelli, D., Cox, P., Badano, J., Blair-Reid, S., Sriram, N., Katsanis, N., Attie-Bitach, T., Afford, S., Copp, A., Kelly, D., Gull, K., and Johnson, C. (2007). The Meckel-Gruber Syndrome proteins MKS1 and meckelin interact and are required for primary cilium formation. Human Molecular Genetics 16 173-186. (PDF)

Devaux, S*., Kelly, S*., Lecordier, L., Wickstead, B., Perez-Morga, D., Pays, E., Vanhamme, L., and Gull, K. (2007). Diversification of function by different isoforms of conventionally shared RNA polymerase subunits. Molecular Biology of the Cell 18 1293-301. (PDF)

2006 ^

Kelly S, Singleton, W, Wickstead B, Ersfeld K and Gull K. (2006) Characterisation and differential nuclear localisation of the Nopp140 and a novel Nopp140-like protein in trypanosomes. Eukaryotic Cell 5, 876-879. (PDF)

Gadelha C, Wickstead B, McKean P, Gull K, (2006) Basal body and flagellum mutants reveal a rotational constraint of the central pair microtubules in the axoneme of trypanosomes. Journal of Cell Science, 119, 2405 - 2413. (PDF)

Vaughan S, Shaw M and Gull K (2006) A post-assembly structural modification to the lumen of flagellar microtubule doublets. Current Biology 16, 449-450. (PDF)

Subramaniam C, Veazy P, Redmond S, Hayes-Sinclair J, Chambers E, Carrington M, Gull K, Matthews K, Horn D and Field M C. (2006) Chromosome-wide analysis by RNAi of growth and viability in the African Eukaryotic Cell 5, 1539 - 1549. (PDF)

Jackson A P, Vaughan S & Gull K (2006) Comparative genomics and concerted evolution of b-tubulin paralogs in Leishmania spp. BMC Genomics 7, 137. http://www.biomedcentral.com/1471-2164/7/137 (PDF)

Davidge J A, Chambers E, Dickinson H A, Towers, K, Ginger M L, McKean P G and Gull K. (2006) Trypanosome IFT mutants provide insight into the motor location for mobility of the flagella connector and flagellarmembrane formation. Journal of Cell Science 119, 3935 - 3943. (PDF)

Jackson A P, Vaughan S & Gull K (2006) Evolution of tubulin gene arrays in Trypanosomatid parasites: genomic restructuring in Leishmania. BMC Genomics 2006, 7:261 http://www.biomedcentral.com/1471-2164/7/261 (PDF)

Woolley, D; Gadelha, C and Gull, K. (2006) Evidence for a sliding-resistance at the tip of the trypansome flagellum Cell Motility and the Cytoskeleton 63 (issue 12) 741-6 (PDF)

Wickstead B, Gull K (2006) A "holistic" kinesin phylogeny reveals new kinesin families and predicts protein functions. Molecular Biology of the Cell 17(4): 1734-1743. (PDF)

Broadhead R, Dawe HR, Farr H, Griffiths S, Hart SR, Portman N, Shaw MK, Ginger ML, Gaskell SJ, McKean PG, Gull K (2006) Flagellar motility is required for the viability of the bloodstream trypanosome. Nature 440(7081): 224-227. (PDF)

2005 ^

Dawe HR, Farr H, Portman N, Shaw MK, Gull K (2005) The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis. Journal of Cell Science 118(23): 5421-5430. (PDF)

Kelly S, Wickstead B, Gull K (2005) An in silico analysis of trypanosornatid RNA polymerases: insights into their unusual transcription. Biochemical Society Transactions 33: 1435-1437. (PDF)

Ersfeld K, Barraclough H, Gull K (2005) Evolutionary relationships and protein domain architecture in an expanded calpain superfamily in kinetoplastid parasites. Journal of Molecular Evolution 61(6): 742-757. (PDF)

El-Sayed NM, Myler PJ, Bartholomeu DC, Nilsson D, Aggarwal G, Tran AN, Ghedin E, Worthey EA, Delcher AL, Blandin G, Westenberger SJ, et al. (2005) The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science 309(5733): 409-415. (PDF)

Berriman M, Ghedin E, Hertz-Fowler C, Blandin G, Renauld H, Bartholomeu DC, Lennard NJ, Caler E, Hamlin NE, Haas B, Bohme W, et al. (2005) The genome of the African trypanosome Trypanosoma brucei. Science 309(5733): 416-422. (PDF)

Sheader K, Vaughan S, Minchin J, Hughes K, Gull K, Rudenko G (2005) Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes. Proceedings of the National Academy of Sciences of the United States of America 102(24): 8716-8721. (PDF)

Morgan GW, Denny PW, Vaughan S, Goulding D, Jeffries TR, Smith DF, Gull K, Field MC (2005) An evolutionarily conserved coiled-coil protein implicated in polycystic kidney disease is involved in basal body duplication and flagellar biogenesis in Trypanosoma brucei. Molecular and Cellular Biology 25(9): 3774-3783. (PDF)

Ginger ML, Ngazoa ES, Pereira CA, Pullen TJ, Kabiri M, Becker K, Gull K, Steverding D (2005) Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei. Journal of Biological Chemistry 280(12): 11781-11789. (PDF)

Gadelha C, Wickstead B, de Souza W, Gull K, Cunha-e-Silva N. (2005) Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa. Eukaryot Cell. 4(3):516-25. (PDF)

2004 ^

Briggs LJ, Davidge JA, Wickstead B, Ginger ML, Gull K (2004) More than one way to build a flagellum: comparative genomics of parasitic protozoa. Current Biology 14(15): R611-R612. (PDF)

Pullen TJ, Ginger ML, Gaskell SJ, Gull K (2004) Protein targeting of an unusual, evolutionarily conserved adenylate kinase to a eukaryotic flagellum. Molecular Biology of the Cell 15(7): 3257-3265. (PDF)

Gadelha C, LeBowitz JH, Manning J, Seebeck T, Gull K (2004) Relationships between the major kinetoplastid paraflagellar rod proteins: a consolidating nomenclature. Molecular and Biochemical Parasitology 136(1): 113-115. (PDF)

Wickstead B, Ersfeld K, Gull K (2004) The small chromosomes of Trypanosoma brucei involved in antigenic variation are constructed around repetitive palindromes. Genome Research 14(6): 1014-1024. (PDF)

Briggs LJ, McKean PG, Baines A, Moreira-Leite F, Davidge J, Vaughan S, Gull K (2004) The flagella connector of Trypanosoma brucei: an unusual mobile transmembrane junction. Journal of Cell Science 117(9): 1641-1651. (PDF)

Motyka SA, Zhao ZX, Gull K, Englund PT (2004) Integration of pZJM library plasmids into unexpected locations in the Trypanosoma brucei genome. Molecular and Biochemical Parasitology 134(1): 163-167. (PDF)

Vaughan S, Wickstead B, Gull K, Addinall SG (2004) Molecular evolution of FtsZ protein sequences encoded within the Genomes of archaea, bacteria, and eukaryota. Journal of Molecular Evolution 58(1): 19-39. (PDF)

2003 ^

Wickstead B, Ersfeld K, Gull K (2003) The mitotic stability of the minichromosomes of Trypanosoma brucei. Molecular and Biochemical Parasitology 132(2): 97-100. (PDF)

Wickstead B, Ersfeld M, Gull K (2003) Repetitive elements in genomes of parasitic protozoa. Microbiology and Molecular Biology Reviews 67(3): 360-+. (PDF)

Gull K (2003) Host-parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies. Current Opinion in Microbiology 6(4): 365-370. (PDF)

Hall N, Berriman M, Lennard NJ, Harris BR, Hertz-Fowler C, Bart-Delabesse EN, Gerrard CS, Atkin RJ, Barron AJ, Bowman S, Bray-Allen SP, et al. (2003) The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism. Nucleic Acids Research 31(16): 4864-4873. (PDF)

Wickstead B, Ersfeld K, Gull K (2003) The frequency of gene targeting in Trypanosoma brucei is independent of target site copy number. Nucleic Acids Research 31(14): 3993-4000. (PDF)

Ogbadoyi EO, Robinson DR, Gull K (2003) A high-order trans-membrane structural linkage is responsible for mitochondrial genome positioning and segregation by flagellar basal bodies in trypanosomes. Molecular Biology of the Cell 14(5): 1769-1779. (PDF)

McKean PG, Baines A, Vaughan S, Gull K (2003) gamma-Tubulin functions in the nucleation of a discrete subset of microtubules in the eukaryotic flagellum. Current Biology 13(7): 598-602. (PDF)

Vaughan S, Gull K (2003) The trypanosome flagellum. Journal of Cell Science 116(5): 757-759. (PDF)

Alsford NS, Navarro M, Jamnadass HR, Dunbar H, Ackroyd M, Murphy NB, Gull K, Ersfeld K (2003) The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei. Molecular Microbiology 47(2): 277-289. (PDF)

2002 ^

Wickstead B, Ersfeld K, Gull K (2002) Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei. Molecular and Biochemical Parasitology 125(1-2): 211-216. (PDF)

Gull K (2002) The cell biology of parasitism in Trypanosoma brucei: Insights and drug targets from genomic approaches? Current Pharmaceutical Design 8(4): 241-256. (PDF)

2001 ^

Tyler KM, Matthews KR, Gull K (2001) Anisomorphic cell division by African trypanosomes. Protist 152(4): 367-378. (PDF)

Navarro M, Gull K (2001) A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei. Nature 414(6865): 759-763. (PDF)

Tyler KM, Higgs PG, Matthews KR, Gull K (2001) Limitation of Trypanosoma brucei parasitaemia results from density-dependent parasite differentiation and parasite killing by the host immune response. Proceedings of the Royal Society of London Series B-Biological Sciences 268(1482): 2235-2243. (PDF)

Moreira-Leite FF, Sherwin T, Kohl L, Gull K (2001) A trypanosome structure involved in transmitting cytoplasmic information during cell division. Science 294(5542): 610-612. (PDF)

Hertz-Fowler C, Ersfeld K, Gull K (2001) CAP5.5, a life-cycle-regulated, cytoskeleton-associated protein is a member of a novel family of calpain-related proteins in Trypanosoma brucei (vol 116, pg 25, 2001). Molecular and Biochemical Parasitology 117(1): 119-119. (PDF)

McKean PG, Vaughan S, Gull K (2001) The extended tubulin superfamily. Journal of Cell Science 114(15): 2723-2733. (PDF)

Gull K (2001) Protist tubulins: new arrivals, evolutionary relationships and insights to cytoskeletal function. Current Opinion in Microbiology 4(4): 427-432. (PDF)

Gull K (2001) The biology of kinetoplastid parasites: insights and challenges from genomics and post-genomics. International Journal for Parasitology 31(5-6): 443-452. (PDF)

Alsford S, Wickstead B, Ersfeld K, Gull K (2001) Diversity and dynamics of the minichromosomal karyotype in Trypanosoma brucei. Molecular and Biochemical Parasitology 113(1): 79-88. (PDF)

Ersfeld K, Gull K (2001) Targeting of cytoskeletal proteins to the flagellum of Trypanosoma brucei. Journal of Cell Science 114(1): 141-148. (PDF)

2000 ^

Bastin P, Pullen TJ, Moreira-Leite FF, Gull K (2000) Inside and outside of the trypanosome flagellum: a multifunctional organelle. Microbes and Infection 2(15): 1865-1874. (PDF)

Lange BMH, Faragher AJ, March P, Gull K (2000). Centriole duplication and maturation in animal cells. Centrosome in Cell Replication and Early Development. 49: 235-249.

Gull K (2000) Genomics and post-genomics in parasitology: genome babble or a real opportunity? Biochemical Society Transactions 28: 541-544. (PDF)

Bastin P, Ellis K, Kohl L, Gull K (2000) Flagellum ontogeny in trypanosomes studied via an inherited and regulated RNA interference system. Journal of Cell Science 113(18): 3321-3328. (PDF)

Vaughan S, Attwood T, Navarro M, Scott V, McKean P, Gull K (2000) New tubulins in protozoal parasites. Current Biology 10(7): R258-R259. (PDF)

Field H, Sherwin T, Smith AC, Gull K, Field MC (2000) Cell-cycle and developmental regulation of TbRAB31 localisation, a GTP-locked Rab protein from Trypanosoma brucei (vol 106, pg 21, 2000). Molecular and Biochemical Parasitology 107(2): 329-330. (PDF)

Ogbadoyi E, Ersfeld K, Robinson D, Sherwin T, Gull K (2000) Architecture of the Trypanosoma brucei nucleus during interphase and mitosis. Chromosoma 108(8): 501-513. (PDF)

Earlier than 2000 ^

Ploubidou A, Robinson DR, Docherty RC, Ogbadoyi EO, Gull K (1999) Evidence for novel cell cycle checkpoints in trypanosomes: kinetoplast segregation and cytokinesis in the absence of mitosis. Journal of Cell Science 112(24): 4641-4650.

Bastin P, Ellis K, Kohl L, Gull K (1999) Expression of an inverted repeat of a target gene leads to specific disappearance of the corresponding mRNA and encoded protein. Molecular Biology of the Cell 10: 104A-104A.

Bastin P, Gull K (1999) Protein targeting and flagellum assembly dynamics revealed by paralysed mutant trypanosomes. Molecular Biology of the Cell 10: 389A-389A.

Bastin P, Pullen TJ, Sherwin T, Gull K (1999) Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1. Journal of Cell Science 112(21): 3769-3777.

Bastin P, MacRae TH, Francis SB, Matthews KR, Gull K (1999) Flagellar morphogenesis: Protein targeting and assembly in the paraflagellar rod of trypanosomes. Molecular and Cellular Biology 19(12): 8191-8200.

Gull K (1999) The cytoskeleton of trypanosomatid parasites. Annual Review of Microbiology 53: 629-+.

Bastin P, Gull K (1999) Assembly and function of complex flagellar structures illustrated by the paraflagellar rod of trypanosomes. Protist 150(2): 113-123.

Maga JA, Sherwin T, Francis S, Gull K, LeBowitz JH (1999) Genetic dissection of the Leishmania paraflagellar rod, a unique flagellar cytoskeleton structure. Journal of Cell Science 112(16): 2753-2763.

Kohl L, Sherwin T, Gull K (1999) Assembly of the paraflagellar rod and the flagellum attachment zone complex during the Trypanosoma brucei cell cycle. Journal of Eukaryotic Microbiology 46(2): 105-109.

Ersfeld K, Melville SE, Gull K (1999) Nuclear and genome organization of Trypanosoma brucei. Parasitology Today 15(2): 58-63.

Field H, Ali BRS, Sherwin T, Gull K, Croft SL, Field MC (1999) TbRab2p, a marker for the endoplasmic reticulum of Trypanosoma brucei, localises to the ERGIC in mammalian cells. Journal of Cell Science 112(2): 147-156.

Clayton C, Adams M, Almeida R, Baltz T, Barrett M, Bastien P, Belli S, Beverley S, Biteau N, Blackwell J, Blaineau C, et al. (1998) Genetic nomenclature for Trypanosomaand Leishmania. Molecular and Biochemical Parasitology 97(1-2): 221-224.

Ngo H, Tschudi C, Gull K, Ullu E (1998) Double-stranded RNA induces mRNA degradation in Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America 95(25): 14687-14692.

March PL, Sibley K, Lange B, Scott V, Gull K (1998) The molecular characterisation of cenexin - A protein the defines the mature centriole. Molecular Biology of the Cell 9: 9A-9A.

Faragher AJ, Lange BMH, Gull K (1998) Investigating the maturation and duplication of mammalian centrioles. Molecular Biology of the Cell 9: 12A-12A.

Field H, Farjah M, Pal A, Gull K, Field MC (1998) Complexity of trypanosomatid endocytosis pathways revealed by Rab4 and Rab5 isoforms in Trypanosoma brucei. Journal of Biological Chemistry 273(48): 32102-32110.

Ersfeld K, Asbeck K, Gull K (1998) Direct visualisation of individual gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation. Chromosoma 107(4): 237-240.

Matthews KR, Gull K (1998) Identification of stage-regulated and differentiation-enriched transcripts during transformation of the African trypanosome from its bloodstream to procyclic form. Molecular and Biochemical Parasitology 95(1): 81-95.

Gull K, Alsford S, Ersfeld K (1998) Segregation of minichromosomes in trypanosomes: implications for mitotic mechanisms. Trends in Microbiology 6(8): 319-323.

Arnot DE, Gull K (1998) The Plasmodium cell-cycle: facts and questions. Annals of Tropical Medicine and Parasitology 92(4): 361-365.

Kohl L, Gull K (1998) Molecular architecture of the trypanosome cytoskeleton. Molecular and Biochemical Parasitology 93(1): 1-9.

Santrich C, Moore L, Sherwin T, Bastin P, Brokaw C, Gull K, LeBowitz JH (1997) A motility function for the paraflagellar rod of Leishmania parasites revealed by PFR-2 gene knockouts. Molecular and Biochemical Parasitology 90(1): 95-109.

Bastin P, Sherwin T, Gull K (1998) Paraflagellar rod is vital for trypanosome motility. Nature 391(6667): 548-548. (PDF)

Matthews KR, Gull K (1997) Commitment to differentiation and cell cycle re-entry are coincident but separable events in the transformation of African trypanosomes from their bloodstream to their insect form. Journal of Cell Science 110: 2609-2618.

Tyler KM, Matthews KR, Gull K (1997) The bloodstream differentiation-division of Trypanosoma brucei studied using mitochondrial markers. Proceedings of the Royal Society of London Series B-Biological Sciences 264(1387): 1481-1490.

Beattie P, Gull K (1997) Cytoskeletal architecture and components involved in the attachment of Trypanosoma congolense epimastigotes. Parasitology 115: 47-55.

Marshall M, Gull K, Jeffries P (1997) Monoclonal antibodies as probes for fungal wall structure during morphogenesis. Microbiology-Uk 143: 2255-2265.

Ersfeld K, Gull K (1997) Partitioning of large and minichromosomes in Trypanosoma brucei. Science 276(5312): 611-614. (PDF)

Ersfeld K, Gull K (1997) The mechanism of genome segregation in Trypanosoma brucei: Evidence for a bifunctional mitotic spindle. European Journal of Cell Biology 72: 240-240.

Scott V, Sherwin T, Gull K (1997) gamma-Tubulin in trypanosomes: Molecular characterisation and localisation to multiple and diverse microtubule organising centres. Journal of Cell Science 110: 157-168.

Lange BMH, Gull K (1996) A structural study of isolated mammalian centrioles using negative staining electron microscopy. Journal of Structural Biology 117(3): 222-226.

Scott V, Ploubidou A, Sherwin T, Gull K (1996) T-tubulin in Trypanosoma brucei. Molecular Biology of the Cell 7: 256-256.

Sibley K, Scott V, Lange B, Gull K (1996) Large-scale isolation of centrosomes using continuous flow centrifugation. Molecular Biology of the Cell 7: 1198-1198.

Butler L, Lange B, Gull K (1996) Centriolar maturation and duplication can be uncoupled from the cell cycle in mammalian cells. Molecular Biology of the Cell 7: 3276-3276.

Ersfeld K, Docherty R, Alsford S, Gull K (1996) A fluorescence in situ hybridisation study of the regulation of histone mRNA levels during the cell cycle of Trypanosoma brucei. Molecular and Biochemical Parasitology 81(2): 201-209.

Lange BMH, Gull K (1996) Structure and function of the centriole in animal cells: Progress and questions. Trends in Cell Biology 6(9): 348-352.

Bastin P, Matthews KR, Gull K (1996) The paraflagellar rod of kinetoplastida: Solved and unsolved questions. Parasitology Today 12(8): 302-307.

Murray K, Ang CE, Gull K, Hickman JA, Dickson AJ (1996) NSO myeloma cell death: Influence of bcl-2 overexpression. Biotechnology and Bioengineering 51(3): 298-304.

Bastin P, Bagherzadeh A, Matthews KR, Gull K (1996) A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei. Molecular and Biochemical Parasitology 77(2): 235-239.

Murray K, Gull K, Dickson AJ (1996) Dichloroacetate increases cell and antibody yields in batch cultures of a hybridoma cell line. Biotechnology and Bioengineering 49(4): 377-382.

Anderson MJ, Gull K, Denning DW (1996) Molecular typing by random amplification of polymorphic DNA and m13 southern hybridization of related paired isolates of Aspergillus fumigatus. Journal of Clinical Microbiology 34(1): 87-93.

Murray K, Gull K, Dickson AJ (1995) Dichloroacetate increases cell and product yields in hybridoma batch cultures. Biochemical Society Transactions 23(4): S585-S585.

Lange BMH, Sherwin T, Hagan T, Gull K (1995) The Basics of Immunofluorescence Video-Microscopy for Mammalian and Microbial Systems (Vol 5, Pg 328, 1995). Trends in Cell Biology 5(9): 375-375.

Lange BMH, Gull K (1995) A Molecular Marker for Centriole Maturation in the Mammalian-Cell Cycle. Journal of Cell Biology 130(4): 919-927. (PDF)

Lange BMH, Sherwin T, Hagan IM, Gull K (1995) The Basics of Immunofluorescence Video-Microscopy for Mammalian and Microbial Systems. Trends in Cell Biology 5(8): 328-332.

Woodward R, Carden MJ, Gull K (1995) Immunological Characterization of Cytoskeletal Proteins Associated with the Basal Body, Axoneme and Flagellum Attachment Zone of Trypanosoma brucei Parasitology 111: 77-85.

Matthews KR, Sherwin T, Gull K (1995) Mitochondrial Genome Repositioning During the Differentiation of the African Trypanosome between Life-Cycle Forms Is Microtubule Mediated. Journal of Cell Science 108: 2231-2239.

Robinson DR, Sherwin T, Ploubidou A, Byard EH, Gull K (1995) Microtubule Polarity and Dynamics in the Control of Organelle Positioning, Segregation, and Cytokinesis in the Trypanosome Cell-Cycle. Journal of Cell Biology 128(6): 1163-1172. (PDF)

Brookman JL, Stott AJ, Cheeseman PJ, Burns NR, Adams SE, Kingsman AJ, Gull K (1995) An Immunological Analysis of Ty1 Virus-Like Particle Structure. Virology 207(1): 59-67. (PDF)

Sherwin T, Gull K. The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations. Philos Trans R Soc Lond B Biol Sci. 1989 Jun 12;323(1218):573-88. (PDF)

Reviews ^

Farr, H. and Gull, K. (2012). Cytokinesis in trypanosomes. Cytoskeleton (Hoboken) 69, 931-41. (PDF)

Hodges, M. E., Wickstead, B., Gull, K., & Langdale, J. A. (2012). The evolution of land plant cilia. New Phytol, 195(3), 526-540. (PDF)

Gull, K. (2010) Boveri and Cancer: prescient views of molecular mechanisms. Notes. Rec. R. Soc. 64(2), 185-7 (PDF)

Daniels, J. P., Gull, K. and Wickstead, B. (2010) Cell biology of the trypanosome genome. Microbiol Mol Biol Rev. 74, 552-569 (PDF)

Portman N, Gull K. (2009) The paraflagellar rod of kinetoplastid parasites: from structure to components and function. Int J Parasitol. 40(2):135-48(PDF)

Sharma R, Gluenz E, Peacock L, Gibson W, Gull K, Carrington M. (2009) The heart of darkness: growth and form of Trypanosoma brucei in the tsetse fly. Trends Parasitol. 25(11):517-24 (PDF)

Ginger ML, Portman N, McKean PG. (2008) Swimming with protists: perception, motility and flagellum assembly. Nat. Rev. Microbiol. 6 (11): 838-850 (PDF)

Gull, K. (2003) Host-parasite interactions and trypanosome morphogenesis: a flagellar pocketful of goodies. Current Opinion in Microbiology 6, 365-370.

Wickstead, W; Ersfeld, K; and Gull, K. (2003) Repetitive elements in the genomes of parasitic protozoa. Microbiology and Molecular Biology Reviews 67, 360-375.

Vaughan, S and Gull, K. (2003) The Trypanosome Flagellum: motility and cell morphogenesis. Journal of Cell Science 116: 757-759.

Gull, K. (2002). "The cell biology of parasitism in Trypanosoma brucei: Insights and drug targets from genomic approaches?" Current Pharmaceutical Design 8(4): 241-256.

Gull, K. (2001). "Protist tubulins: new arrivals, evolutionary relationships and insights to cytoskeletal function." Current Opinion in Microbiology 4(4): 427-432.

Gull, K. (2001). "The biology of kinetoplastid parasites: insights and challenges from genomics and post-genomics." International Journal for Parasitology 31(5-6): 443-452.

Bastin, P., T. J. Pullen, et al. (2000). "Inside and outside of the trypanosome flagellum: a multifunctional organelle." Microbes and Infection 2(15): 1865-1874.

Lange, B. M. H., A. J. Faragher, et al. (2000). Centriole duplication and maturation in animal cells. Centrosome in Cell Replication and Early Development. 49: 235-249.

Gull, K. (2000). "Genomics and post-genomics in parasitology: genome babble or a real opportunity?" Biochemical Society Transactions 28: 541-544.

Gull, K. (1999). "The cytoskeleton of trypanosomatid parasites." Annual Review of Microbiology 53: 629-+.

Bastin, P. and K. Gull (1999). "Assembly and function of complex flagellar structures illustrated by the paraflagellar rod of trypanosomes." Protist 150(2): 113-123.

Bastin, P., K. R. Matthews, et al. (1996). "The paraflagellar rod of kinetoplastida: Solved and unsolved questions." Parasitology Today 12(8): 302-307.

McKean, P. G., S. Vaughan, et al. (2001). "The extended tubulin superfamily." Journal of Cell Science 114(15): 2723-2733.

Ersfeld, K., S. E. Melville, et al. (1999). "Nuclear and genome organization of Trypanosoma brucei." Parasitology Today 15(2): 58-63.

Gull, K., S. Alsford, et al. (1998). "Segregation of minichromosomes in trypanosomes: implications for mitotic mechanisms." Trends in Microbiology 6(8): 319-323.

Lange, B. M. H. and K. Gull (1996). "Structure and function of the centriole in animal cells: Progress and questions." Trends in Cell Biology 6(9): 348-352.

By Richard Wheeler, 2011
Header image: Dividing bloodstream form Trypanosoma brucei, taken by Helen Banks