Transcription factories in a Hela cell [from Cook PR (1999) Science 284, 1790]

Nuclear Structure and Function Research Group

Movies / Printing a microfluidic circuit in seconds
Overview  
    Conventional microfluidic circuits take days to make. The introduction of 'Freestyle Fluidics' changes this (Walsh EJ et al, 2017, Nat Commun 8, 816).
    Now you can make a circuit in much the same time as it takes to draw that circuit on a piece of paper.
    This YouTube movie runs in real time as a ‘pen’ prints a circuit containing cell-growth medium + blue dye on a 6 cm Petri dish. 'Conduits' have base widths of about 500 microns, and maximum heights of about 150 microns.
    Inter-facial forces are powerful at the micro-scale, and they firmly 'pin' the circuit to the dish (in the same way they pin raindrops to window panes).

 
 

 

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