Publications 1973-1990 (Peter R Cook's group)

Cook, P.R. (1973). Hypothesis on differentiation and the inheritance of gene superstructure. Nature 245, 23-25. [PubMed]

Cook, P.R. (1974). On the inheritance of differentiated traits. Biol. Rev. 49, 51-84.

Cook, P.R. (1975). Linkage of the loci for glucose-6-phosphate dehydrogenase and for inosinic acid pyrophosphorylase to the X chromosome of the field-vole Microtus agrestis. J. Cell Sci. 17, 95-112. [PubMed]

Cook, P.R., and Brazell, I.A. (1975). Supercoils in human DNA. J. Cell Sci. 19, 261-279. [PubMed]

Cook, P.R., and Brazell, I.A. (1976). Conformational constraints in nuclear DNA. J. Cell Sci. 22, 287-302. [PubMed]

Cook, P.R., Brazell, I.A., and Jost, E. (1976). Characterization of nuclear structures containing superhelical DNA. J. Cell Sci. 22, 303-324. [PubMed]

Cook, P.R., and Brazell, I.A. (1976). Detection and repair of single-strand breaks in nuclear DNA. Nature 263, 679-682. [PubMed]

Cook, P.R., and Brazell, I.A. (1977). The superhelical density of nuclear DNA from human cells. Eur. J. Biochem. 74, 527-531. [PubMed]

Cook, P.R., and Brazell, I.A. (1977). Supercoils in nuclear DNA and the repair of radiation damage. Mut. Res. 46, 111-112.

Colman, A., and Cook, P.R. (1977). Transcription of superhelical DNA from cell nuclei. Eur. J. Biochem. 76, 63-78. [PubMed]

Levin, J.M., Jost, E., and Cook, P.R. (1978). The dissociation of nuclear proteins from superhelical DNA. J. Cell Sci. 29, 103-116. [PubMed]

Cook, P.R., Brazell, I.A., Pawsey, S.A., and Giannelli, F. (1978). Changes induced by ultraviolet light in the superhelical DNA of lymphocytes from subjects with xeroderma pigmentosum and normal controls. J. Cell Sci. 29, 117-127. [PubMed]

Cook, P.R., and Brazell, I.A. (1978). Spectrofluorometric measurement of the binding of ethidium to superhelical DNA from cell nuclei. Eur. J. Biochem. 84, 465-477. [PubMed]

Warren, A.C., and Cook, P.R. (1978). Supercoiling of DNA and nuclear conformation during the cell cycle. J. Cell Sci. 30, 211-226. [PubMed]

McCready, S.J., Akrigg, A., and Cook, P.R. (1979). Electron microscopy of intact nuclear DNA from human cells. J. Cell Sci. 39, 53-62. [PubMed]

Akrigg, A., and Cook, P.R. (1980). DNA gyrase stimulates transcription. Nucl. Acids Res. 8, 845-854. [PubMed]

Cook, P.R., and Brazell, I.A. (1980). Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage. Nucl. Acids Res. 8, 2895-2906. [PubMed]

McCready, S.J., Godwin, J., Mason, D.W., Brazell, I.A., and Cook, P.R. (1980). DNA is replicated at the nuclear cage. J. Cell Sci. 46, 365-386. [PubMed]

Levin, J.M., and Cook, P.R. (1981). Conformational changes induced by salt in complexes of histones and superhelical nuclear DNA. J. Cell Sci. 50, 199-208. [PubMed]

Levin, J.M., and Cook, P.R. (1981). Reconstruction of complexes of histones and superhelical nuclear DNA. J. Cell Sci. 50, 209-224. [PubMed]

Jackson, D.A., McCready, S.J., and Cook, P.R. (1981). RNA is synthesised at the nuclear cage. Nature 292, 552-555. [PubMed]

McCready, S.J., Jackson, D.A., and Cook, P.R. (1982). Attachment of superhelical DNA to the nuclear cage during replication and transcription. Prog. Mut. Res. 4, 113-130.

Jackson, D.A., Caton, A.J., McCready S.J., and Cook, P.R. (1982). Influenza virus RNA is synthesised at fixed sites in the nucleus. Nature 296, 366-368. [PubMed]

Cook, P.R. Lang, J., Hayday, A., Lania, L., Fried, M., Chiswell, D.J., and Wyke, J.A. (1982). Active viral genes in transformed cells lie close to the nuclear cage. EMBO J. 1, 447-452. [PubMed]

Jackson, D.A., and Patel, S.B. (1982). Nuclear organization - does the sub-structure play a crucial role? Trends Biochem. Sci. 7, 272-274.

Patel, S.B., and Cook, P.R. (1983). The DNA-protein cross: a method for detecting specific DNA-protein complexes in crude mixtures. EMBO J. 2, 137-142. [PubMed]

Cook, P.R., and Lang, J. (1984). The spatial organization of sequences involved in initiation and termination of eukaryotic DNA replication. Nucl. Acids Res. 12, 1069-1075. [PubMed]

Cook, P.R. (1984). A general method for isolating intact nuclear DNA. EMBO J. 3, 1837-1842. [PubMed]

McCready, S.J., and Cook, P.R. (1984). Lesions induced in DNA by ultra-violet light are repaired at the nuclear cage. J. Cell Sci. 70, 189-196. [PubMed]

Jackson, D.A., Patel, S.B., and Cook, P.R. (1984). Attachment of repeated sequences to the nuclear cage. Nucl. Acids Res. 12, 6709-6726. [PubMed]

Jackson, D.A., McCready, S.J., and Cook, P.R. (1984). Replication and transcription depend on attachment of DNA to the nuclear cage. J. Cell Sci. Suppl. 1, 59-79. [PubMed]

Cook, P.R., and Laskey, R.A. (editors), (1984). 'Higher order structure in the nucleus'. Proceedings of the First British Society for Cell Biology - Company of Biologists Symposium held in Manchester, April, 1984. J. Cell Sci. Suppl. 1.

Dyson, P.J., Cook, P.R., Searle, S., and Wyke, J.A. (1985). The chromatin structure of Rous sarcoma proviruses is changed by factors that act in trans in cell hybrids. EMBO J. 4, 413-420. [PubMed]

McCready, S.J., and Cook, P.R. (1985). Unscheduled DNA synthesis takes place at the nuclear cage. Br. J. Cancer 51, 604.

Jackson, D.A., and Cook, P.R. (1985). A general method for preparing chromatin containing intact DNA. EMBO J. 4, 913-918. [PubMed]

Jackson, D.A., and Cook, P.R. (1985). Transcription occurs at a nucleoskeleton. EMBO J. 4, 919-925. [PubMed]

Jackson, D.A., and Cook, P.R. (1986). Replication occurs at a nucleoskeleton. EMBO J. 5, 1403-1410. [PubMed]

Whittaker, J., Lang, J., Cook, P.R., Aspinall, S., McCready, S.J., and Cox, B.S. (1986). Part of the human ribosomal RNA locus stabilizes a plasmid in yeast. Nucl. Acids Res. 14, 5683-5692. [PubMed]

Jackson, D.A., and Cook, P.R. (1986). A cell-cycle dependent DNA polymerase activity that replicates intact DNA in chromatin. J. Mol. Biol. 192, 65-76. [PubMed]

Jackson, D.A., and Cook, P.R. (1986). Different populations of DNA polymerase α in Hela cells. J. Mol. Biol. 192, 77-86. [PubMed]

Jackson, D.A. (1986). Nucleoids. In 'Nuclear Structures: isolation and characterization' pp 14-33. Ed. MacGillivray A.J., and Birnie G.D. Butterworths, London.

Jackson, D.A. (1986). Organization beyond the gene. Trends Biochem. Sci. 11, 249-252.

Jackson, D.A., and Cook, P.R. (1987). The nucleoskeleton: active site of transcription and replication. In 'Modern Trends in Human Leukemia VII', edited by Neth, R., Gallo, R.C., Greaves, M.F., and Kabisch, H., pp 299-303, Springer-Verlag, Berlin. Also published as Jackson, D.A., and Cook, P.R. (1987). The nucleoskeleton: active site of transcription and replication. Haematol. Blood Transfus. 31, 299-303. [PubMed]

Cook, P.R., and Jackson, D.A. (1988). The nucleoskeleton: active site of transcription or artifact? In 'Chromosomes and Chromatin' Vol. III, edited by Adolph, K.W., pp 97-118, CRC Press, Baton Rouge, Florida.

Cook, P.R. (1988). The nucleoskeleton: artefact, passive framework or active site? J. Cell Sci. 90, 1-6. [PubMed]

Jackson, D.A., Yuan, J., and Cook, P.R. (1988). A gentle method for preparing cyto- and nucleo-skeletons and associated chromatin. J. Cell Sci. 90, 365-378. [PubMed]

Jackson, D.A., and Cook, P.R. (1988). Visualization of a filamentous nucleoskeleton with a 23 nm axial repeat. EMBO J. 7, 3667-3677. [PubMed]

Dear, P.H., and Cook, P.R. (1989). Happy mapping: a proposal for linkage mapping the human genome. Nucl. Acids Res. 17, 6795-6807. [PubMed]

Cook, P.R. (1989). The nucleoskeleton and the topology of transcription. Eur. J. Biochem. 185, 487-501. [PubMed]

Jackson, D.A., Pearson, C.K., Fraser, D.C., Prise, K.M., and Wong, S. Y. (1989). Methotrexate-induced morphological changes mimic those seen after heat-shock. J. Cell Sci. 92, 37-49. [PubMed]

Briggs, D., Jackson, D., Whitelaw, E., and Proudfoot, N.J. (1989). Direct demonstration of termination signals for RNA polymerase II from the sea urchin H2A histone gene. Nucl. Acids Res. 17, 8061-8071.

Jackson, D.A., Dickinson, P., and Cook, P.R. (1990). The size of chromatin loops in HeLa cells. EMBO J. 9, 567-571. [PubMed]

Cook, P.R. (1990). How mobile are active RNA polymerases? J. Cell Sci. 96, 189-192. [PubMed]

Dickinson, P., Cook, P.R., and Jackson, D.A. (1990). Active RNA polymerase I is fixed within the nucleus of HeLa cells. EMBO J. 9, 2207-2214. [PubMed]

Jackson, D.A., Dickinson, P., and Cook, P.R. (1990). Attachment of DNA to the nucleoskeleton of HeLa cells examined using physiological conditions. Nucl. Acids Res. 18, 4385-4393. [PubMed]

Jackson, D.A. (1990). The organization of replication centres in higher eukaryotes. BioEssays 12, 87-89. [PubMed]

Jackson, D.A. (1990). Does butylphenyl-deoxyguanosine triphosphate differentially inhibit DNA polymerase a and d activities in permeabilised HeLa cells? Nucl. Acids Res. 18, 753-758. [PubMed]]

	Nuclear Structure and Function Research Group
	Peter R Cook's group at The Sir William Dunn School of Pathology University of Oxford
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Quick links Contacts, visiting Oxford Model for all genomes EpiGenSys Students: Lecture notes Reading lists Resources Movies: 1. Transcription cycle 2. Mobile/fixed polymerases? Catalogs: 1. Proteomes of factories 2. Engaged polymerases	Publications / 1973 - 1990
	Cook, P.R. (1973). Hypothesis on differentiation and the inheritance of gene superstructure. Nature 245, 23-25. [PubMed] Cook, P.R. (1974). On the inheritance of differentiated traits. Biol. Rev. 49, 51-84. Cook, P.R. (1975). Linkage of the loci for glucose-6-phosphate dehydrogenase and for inosinic acid pyrophosphorylase to the X chromosome of the field-vole Microtus agrestis. J. Cell Sci. 17, 95-112. [PubMed] Cook, P.R., and Brazell, I.A. (1975). Supercoils in human DNA. J. Cell Sci. 19, 261-279. [PubMed] Cook, P.R., and Brazell, I.A. (1976). Conformational constraints in nuclear DNA. J. Cell Sci. 22, 287-302. [PubMed] Cook, P.R., Brazell, I.A., and Jost, E. (1976). Characterization of nuclear structures containing superhelical DNA. J. Cell Sci. 22, 303-324. [PubMed] Cook, P.R., and Brazell, I.A. (1976). Detection and repair of single-strand breaks in nuclear DNA. Nature 263, 679-682. [PubMed] Cook, P.R., and Brazell, I.A. (1977). The superhelical density of nuclear DNA from human cells. Eur. J. Biochem. 74, 527-531. [PubMed] Cook, P.R., and Brazell, I.A. (1977). Supercoils in nuclear DNA and the repair of radiation damage. Mut. Res. 46, 111-112. Colman, A., and Cook, P.R. (1977). Transcription of superhelical DNA from cell nuclei. Eur. J. Biochem. 76, 63-78. [PubMed] Levin, J.M., Jost, E., and Cook, P.R. (1978). The dissociation of nuclear proteins from superhelical DNA. J. Cell Sci. 29, 103-116. [PubMed] Cook, P.R., Brazell, I.A., Pawsey, S.A., and Giannelli, F. (1978). Changes induced by ultraviolet light in the superhelical DNA of lymphocytes from subjects with xeroderma pigmentosum and normal controls. J. Cell Sci. 29, 117-127. [PubMed] Cook, P.R., and Brazell, I.A. (1978). Spectrofluorometric measurement of the binding of ethidium to superhelical DNA from cell nuclei. Eur. J. Biochem. 84, 465-477. [PubMed] Warren, A.C., and Cook, P.R. (1978). Supercoiling of DNA and nuclear conformation during the cell cycle. J. Cell Sci. 30, 211-226. [PubMed] McCready, S.J., Akrigg, A., and Cook, P.R. (1979). Electron microscopy of intact nuclear DNA from human cells. J. Cell Sci. 39, 53-62. [PubMed] Akrigg, A., and Cook, P.R. (1980). DNA gyrase stimulates transcription. Nucl. Acids Res. 8, 845-854. [PubMed] Cook, P.R., and Brazell, I.A. (1980). Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage. Nucl. Acids Res. 8, 2895-2906. [PubMed] McCready, S.J., Godwin, J., Mason, D.W., Brazell, I.A., and Cook, P.R. (1980). DNA is replicated at the nuclear cage. J. Cell Sci. 46, 365-386. [PubMed] Levin, J.M., and Cook, P.R. (1981). Conformational changes induced by salt in complexes of histones and superhelical nuclear DNA. J. Cell Sci. 50, 199-208. [PubMed] Levin, J.M., and Cook, P.R. (1981). Reconstruction of complexes of histones and superhelical nuclear DNA. J. Cell Sci. 50, 209-224. [PubMed] Jackson, D.A., McCready, S.J., and Cook, P.R. (1981). RNA is synthesised at the nuclear cage. Nature 292, 552-555. [PubMed] McCready, S.J., Jackson, D.A., and Cook, P.R. (1982). Attachment of superhelical DNA to the nuclear cage during replication and transcription. Prog. Mut. Res. 4, 113-130. Jackson, D.A., Caton, A.J., McCready S.J., and Cook, P.R. (1982). Influenza virus RNA is synthesised at fixed sites in the nucleus. Nature 296, 366-368. [PubMed] Cook, P.R. Lang, J., Hayday, A., Lania, L., Fried, M., Chiswell, D.J., and Wyke, J.A. (1982). Active viral genes in transformed cells lie close to the nuclear cage. EMBO J. 1, 447-452. [PubMed] Jackson, D.A., and Patel, S.B. (1982). Nuclear organization - does the sub-structure play a crucial role? Trends Biochem. Sci. 7, 272-274. Patel, S.B., and Cook, P.R. (1983). The DNA-protein cross: a method for detecting specific DNA-protein complexes in crude mixtures. EMBO J. 2, 137-142. [PubMed] Cook, P.R., and Lang, J. (1984). The spatial organization of sequences involved in initiation and termination of eukaryotic DNA replication. Nucl. Acids Res. 12, 1069-1075. [PubMed] Cook, P.R. (1984). A general method for isolating intact nuclear DNA. EMBO J. 3, 1837-1842. [PubMed] McCready, S.J., and Cook, P.R. (1984). Lesions induced in DNA by ultra-violet light are repaired at the nuclear cage. J. Cell Sci. 70, 189-196. [PubMed] Jackson, D.A., Patel, S.B., and Cook, P.R. (1984). Attachment of repeated sequences to the nuclear cage. Nucl. Acids Res. 12, 6709-6726. [PubMed] Jackson, D.A., McCready, S.J., and Cook, P.R. (1984). Replication and transcription depend on attachment of DNA to the nuclear cage. J. Cell Sci. Suppl. 1, 59-79. [PubMed] Cook, P.R., and Laskey, R.A. (editors), (1984). 'Higher order structure in the nucleus'. Proceedings of the First British Society for Cell Biology - Company of Biologists Symposium held in Manchester, April, 1984. J. Cell Sci. Suppl. 1. Dyson, P.J., Cook, P.R., Searle, S., and Wyke, J.A. (1985). The chromatin structure of Rous sarcoma proviruses is changed by factors that act in trans in cell hybrids. EMBO J. 4, 413-420. [PubMed] McCready, S.J., and Cook, P.R. (1985). Unscheduled DNA synthesis takes place at the nuclear cage. Br. J. Cancer 51, 604. Jackson, D.A., and Cook, P.R. (1985). A general method for preparing chromatin containing intact DNA. EMBO J. 4, 913-918. [PubMed] Jackson, D.A., and Cook, P.R. (1985). Transcription occurs at a nucleoskeleton. EMBO J. 4, 919-925. [PubMed] Jackson, D.A., and Cook, P.R. (1986). Replication occurs at a nucleoskeleton. EMBO J. 5, 1403-1410. [PubMed] Whittaker, J., Lang, J., Cook, P.R., Aspinall, S., McCready, S.J., and Cox, B.S. (1986). Part of the human ribosomal RNA locus stabilizes a plasmid in yeast. Nucl. Acids Res. 14, 5683-5692. [PubMed] Jackson, D.A., and Cook, P.R. (1986). A cell-cycle dependent DNA polymerase activity that replicates intact DNA in chromatin. J. Mol. Biol. 192, 65-76. [PubMed] Jackson, D.A., and Cook, P.R. (1986). Different populations of DNA polymerase α in Hela cells. J. Mol. Biol. 192, 77-86. [PubMed] Jackson, D.A. (1986). Nucleoids. In 'Nuclear Structures: isolation and characterization' pp 14-33. Ed. MacGillivray A.J., and Birnie G.D. Butterworths, London. Jackson, D.A. (1986). Organization beyond the gene. Trends Biochem. Sci. 11, 249-252. Jackson, D.A., and Cook, P.R. (1987). The nucleoskeleton: active site of transcription and replication. In 'Modern Trends in Human Leukemia VII', edited by Neth, R., Gallo, R.C., Greaves, M.F., and Kabisch, H., pp 299-303, Springer-Verlag, Berlin. Also published as Jackson, D.A., and Cook, P.R. (1987). The nucleoskeleton: active site of transcription and replication. Haematol. Blood Transfus. 31, 299-303. [PubMed] Cook, P.R., and Jackson, D.A. (1988). The nucleoskeleton: active site of transcription or artifact? In 'Chromosomes and Chromatin' Vol. III, edited by Adolph, K.W., pp 97-118, CRC Press, Baton Rouge, Florida. Cook, P.R. (1988). The nucleoskeleton: artefact, passive framework or active site? J. Cell Sci. 90, 1-6. [PubMed] Jackson, D.A., Yuan, J., and Cook, P.R. (1988). A gentle method for preparing cyto- and nucleo-skeletons and associated chromatin. J. Cell Sci. 90, 365-378. [PubMed] Jackson, D.A., and Cook, P.R. (1988). Visualization of a filamentous nucleoskeleton with a 23 nm axial repeat. EMBO J. 7, 3667-3677. [PubMed] Dear, P.H., and Cook, P.R. (1989). Happy mapping: a proposal for linkage mapping the human genome. Nucl. Acids Res. 17, 6795-6807. [PubMed] Cook, P.R. (1989). The nucleoskeleton and the topology of transcription. Eur. J. Biochem. 185, 487-501. [PubMed] Jackson, D.A., Pearson, C.K., Fraser, D.C., Prise, K.M., and Wong, S. Y. (1989). Methotrexate-induced morphological changes mimic those seen after heat-shock. J. Cell Sci. 92, 37-49. [PubMed] Briggs, D., Jackson, D., Whitelaw, E., and Proudfoot, N.J. (1989). Direct demonstration of termination signals for RNA polymerase II from the sea urchin H2A histone gene. Nucl. Acids Res. 17, 8061-8071. Jackson, D.A., Dickinson, P., and Cook, P.R. (1990). The size of chromatin loops in HeLa cells. EMBO J. 9, 567-571. [PubMed] Cook, P.R. (1990). How mobile are active RNA polymerases? J. Cell Sci. 96, 189-192. [PubMed] Dickinson, P., Cook, P.R., and Jackson, D.A. (1990). Active RNA polymerase I is fixed within the nucleus of HeLa cells. EMBO J. 9, 2207-2214. [PubMed] Jackson, D.A., Dickinson, P., and Cook, P.R. (1990). Attachment of DNA to the nucleoskeleton of HeLa cells examined using physiological conditions. Nucl. Acids Res. 18, 4385-4393. [PubMed] Jackson, D.A. (1990). The organization of replication centres in higher eukaryotes. BioEssays 12, 87-89. [PubMed] Jackson, D.A. (1990). Does butylphenyl-deoxyguanosine triphosphate differentially inhibit DNA polymerase a and d activities in permeabilised HeLa cells? Nucl. Acids Res. 18, 753-758. [PubMed]] Top \| Home \| Maintained by Peter Cook \|

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