Transcription factories in a Hela cell [from Cook PR (1999) Science 284, 1790]

Nuclear Structure and Function Research Group

Publications / 2006 - 2010

Bartlett, J., Blagojevic, J., Carter, D., Eskiw, C., Fromaget, M., Job, C., Shamsher, M., Faro Trindade, I, Xu, M., and Cook, P.R. (2006).  Specialized transcription factories.  Biochem. Soc. Symp. 73, 67-75. [PubMed]

Bon, M., Marenduzzo, D., Cook, P.R. (2006).  Modeling a self-avoiding chromatin loop: relation to the packing problem, action-at-a-distance, and nuclear context.  Structure 14, 197–204. [PubMed]

Marenduzzo, D., Micheletti, C., and Cook, P.R. (2006). Entropy-driven genome organization. Biophys. J. 90, 3712-3721. [PubMed]

Bon, M., McGowan, S., and Cook, P.R. (2006). Many expressed genes in bacteria and yeast are transcribed only once per cell cycle. FASEB J. 20, 1721-1723. [PubMed] [Supporting on-line information; search for a gene of interest; downloads]

Faro-Trindade, I., and Cook, P.R. (2006). A conserved organization of transcription during embryonic stem cell differentiation and in cells with high C value. Mol. Biol. Cell 17, 2910-2920. [PubMed]

Toan, N.M., Marenduzzo, D., Cook, P.R., and Micheletti, C. (2006). Depletion effects and loop formation in self-avoiding polymers. Phys. Rev. Lett. 97, 178302. [PubMed]

Faro-Trindade, I., and Cook, P.R. (2006). Transcription factories: structures conserved during differentiation and evolution. Biochem. Soc. Trans. 34, 1133-1137. [PubMed]

Marenduzzo, D., Finan, K., and Cook, P.R. (2006). The depletion attraction: an underappreciated force driving cellular organization. J. Cell Biol. 175, 681-686. [PubMed]

Kimura, H., and Cook, P.R. (2007). Dynamic chromatin loops and the regulation of gene expression. In ‘Nuclear dynamics: molecular biology and visualization of the nucleus’; K. Nagata, and T. Takeyasu, Eds; Springer,Japan.

Marenduzzo, D., Faro-Trindade, I., and Cook, P.R. (2007). What are the molecular ties that maintain genomic loops? Trends Genet. 23, 126-133. [PubMed]

Fromaget, M., and Cook, P.R. (2007). Photobleaching reveals complex effects of inhibitors on transcribing RNA polymerase II in living cells. Exp. Cell Res. 313, 3026-3033. [PubMed]

Escargueil A.E., Poindessous, V., Soares, D.G., Sarasin, A., Cook, P.R., and Larsen, A.K. (2008). Influence of irofulven, a transcription-coupled repair-specific antitumor agent, on RNA polymerase activity: stability and dynamics in living mammalian cells. J. Cell Sci. 121, 1275-1283. [PubMed]

Xu, M., and Cook, P.R. (2008). Similar active genes cluster in specialized transcription factories. J. Cell Biol. 181, 615-623. [PubMed]

Eskiw, C.H., Rapp, A., Carter, D.R.F., and Cook, P.R. (2008). RNA polymerase II activity is located on the surface of ~87 nm protein-rich transcription factories. J. Cell Sci. 121, 1999-2007. [PubMed]

Carter, D.R.F., Eskiw, C., and Cook, P.R. (2008). Transcription factories. Biochem. Soc. Trans. 36, 585-589. [PubMed]

Xu, M., and Cook, P.R. (2008). The role of specialized transcription factories in chromosome pairing. Biochem. Biophys. Acta 1783, 2155-2160. [PubMed]

Cook, P.R., and Marenduzzo, D. (2009). Entropic organization of interphase chromosomes. J. Cell Biol. 186, 825-834. [PubMed]

Wada, Y., Ohta, Y., Xu, M., Tsutsumi, S., Minami, T., Inoue, K., Komura, D., Kitakami, J., Oshida, N., Papantonis, A., Izumi, A., Kobayashi, M., Meguro, H., Kanki, Y., Mimura, I., Yamamoto, K., Mataki, C., Hamakubo, T., Shirahige, K., Aburatani, H., Kimura, H., Kodama, T., Cook. P.R., and Ihara, S. (2009). Visualizing a wave of transcription as it sweeps along activated human genes. Proc. Natl. Acad. Sci. USA, 106, 18357-18361. [PubMed]

Cook, P.R. (2010). A model for all genomes; the role of transcription factories. J. Mol. Biol. 395, 1–10. [PubMed] [pdf]

Papantonis, A., and Cook, P.R. (2010). Genome architecture and the role of transcription. Curr. Opin. Cell. Biol. 22, 1–6. [PubMed]

Papantonis, A., Larkin, J.D., Wada, Y., Ohta, Y., Ihara, S., Kodama, T., and Cook, P.R. (2010). Active RNA polymerases: mobile or immobile molecular machines? PLoS Biol. 8, e1000419. [PubMed] [pdf] [supporting movie]

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