Sir William Dunn School of Pathology

University of Oxford

T Cell Signalling Group

T cell activation triggered by peptide/MHC recognition on an Antigen Presenting Cell (APC). Scanning electron microscopy images illustrating the dramatic morphological changes following antigen recognition. From left to right: no antigen, 5 and 20 minutes after T cell-APC contact (From J. Immunol. 2001, 166:5540-49).